Analytical Data
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Gene name
Ifnar1
- Application
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Alternative Names
IFNAR2;IFNABR;IFNARB;Interferon alpha/beta receptor 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P17181
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Expression Region
28-436aa
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AA Sequence
KNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLS GCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQ IGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVE ERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVEN ELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKW KQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTE IQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENT SNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCE KTKPGNTSK
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Molecular Weight
74 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of the IFNAR1 recombinant protein is rooted in the broader field of immunology and antiviral research. IFNAR1, or Interferon Alpha/Beta Receptor Subunit 1, plays a critical role in the interferon signaling pathway, which is essential for the immune response against viral infections. Interferons are cytokines that trigger a protective antiviral state in cells, thus limiting viral replication and spread. Research on IFNAR1 has gained momentum as scientists seek to understand its structure, function, and potential as a therapeutic target. Recombinant protein production of IFNAR1 allows for detailed biochemical studies enabling researchers to elucidate its interaction with interferons and downstream signaling pathways. This information is vital for developing new therapeutics to enhance immune responses, particularly in viral infections and cancer. Additionally, understanding the role of IFNAR1 in regulatory processes can shed light on autoimmune diseases where interferon signaling may be dysregulated. Overall, the investigation of IFNAR1 recombinant protein provides significant insights into the complexities of the immune system and holds promise for novel therapeutic strategies.
