Analytical Data
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基因名
Ccl28
- Application
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别名
C C motif chemokine ligand 28; C-C motif chemokine 28
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRJ3
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表达区间
20-127aa
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氨基酸序列
SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY
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分子量
12.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Ccl28, also known as chemokine ligand 28, is a member of the CC chemokine family that plays a crucial role in immune response and inflammation. It is primarily expressed in mucosal tissues, including the gut and salivary glands, where it attracts immune cells to sites of infection and inflammation. Researchers have shown that Ccl28 is involved in recruiting specific subsets of T cells and memory B cells, thereby facilitating the development of an effective immune response in mucosal surfaces. Its importance is highlighted in various disease contexts, such as autoimmune disorders, allergies, and infections, where its expression may be upregulated. The recombinant Ccl28 protein has been produced for research purposes to better understand its biochemical properties and functional mechanisms. This protein enables scientists to explore Ccl28's therapeutic potential, including its application in vaccine development and treatment strategies targeting mucosal immunity. Fresh insights into Ccl28 signaling pathways may pave the way for novel interventions aimed at modulating immune responses, enhancing vaccine efficacy, or developing new therapeutic strategies for diseases that involve aberrant immune activation. The study of Ccl28 and its recombinant forms is crucial for advancing our understanding of mucosal immunology and could lead to significant breakthroughs in the management of various health conditions.












