Analytical Data
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Gene name
CTRB2
- Application
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Alternative Names
CTRB2；Chymotrypsinogen B2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6GPI1
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Expression Region
19-263aa
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AA Sequence
CG VPAIHPVLSG LSRIVNGEDA VPGSWPWQVS LQDKTGFHFC GGSLISEDWV VTAAHCGVRT SDVVVAGEFD QGSDEENIQV LKIAKVFKNP KFSILTVNND ITLLKLATPA RFSQTVSAVC LPSADDDFPA GTLCATTGWG KTKYNANKTP DKLQQAALPL LSNAECKKSW GRRITDVMIC AGASGVSSCM GDSGGPLVCQ KDGAWTLVGI VSWGSRTCST TTPAVYARVA KLIPWVQKIL AAN
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Molecular Weight
27.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTRB2, or chymotrypsinogen B2, is a serine protease that plays a significant role in the digestive processes of various organisms, particularly in the pancreas. Research into CTRB2 has gained traction due to its potential implications in both physiological and pathological conditions, including its involvement in metabolic diseases and inflammatory responses. Recent studies have identified CTRB2's various substrates and targets, suggesting it plays a crucial role beyond digestion, potentially influencing cellular signaling pathways and immune responses. The recombinant production of CTRB2 protein allows for detailed studies of its enzymatic activity, structural properties, and interactions with inhibitors. This recombinant protein provides a valuable tool for elucidating its biological functions and mechanisms at a molecular level, facilitating the development of therapeutic strategies to modulate its activity in disease contexts. Understanding the structure-function relationship of CTRB2 through recombinant techniques can lead to advancements in drug design and highlight its therapeutic potential, particularly in conditions where proteolytic balance is disrupted. As research continues to uncover the multifaceted roles of CTRB2, its recombinant protein will be essential for further studies, paving the way for innovative approaches in treating related disorders.
