Analytical Data
-
Gene name
Ccl9
- Application
-
Alternative Names
Ccl9；Toll-like receptor 6
-
Species
Mouse
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P51670
-
Expression Region
22-122aa
-
AA Sequence
QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
-
Molecular Weight
11.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Ccl9, also known as C-C motif chemokine 9, is a chemokine that plays a crucial role in immune responses, particularly in the recruitment of monocytes and T cells to sites of inflammation. It is primarily expressed in various tissues including the lungs, liver, and intestines, and is instrumental in mediating the migration of immune cells during inflammatory responses. Recent studies have highlighted its involvement in various pathological conditions, such as autoimmune diseases, cancer, and chronic inflammatory disorders. Given its significant role in modulating immune activity, Ccl9 has emerged as a promising target for therapeutic interventions. Researchers are increasingly focused on developing recombinant Ccl9 proteins to better understand its molecular mechanisms and its potential as a biomarker or therapeutic agent. These recombinant proteins can be utilized in various assays to evaluate their effects on immune cell function, migration, and polarization. Additionally, exploration of Ccl9's interactions with its receptors could unveil new pathways for drug development aimed at mitigating unwanted inflammation or enhancing anti-tumor immunity. Understanding the functionality of Ccl9 through recombinant protein studies not only provides insights into its biological roles but also aids in the design of innovative strategies for treating diseases characterized by dysregulated immune responses. As research progresses, the therapeutic implications of manipulating Ccl9 signaling pathways continue to attract interest within the scientific community, offering hope for novel treatments in the realm of immunology and beyond.
