Analytical Data
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基因名
Ccl9
- Application
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别名
Ccl9;Toll-like receptor 6
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51670
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表达区间
22-122aa
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氨基酸序列
QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
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分子量
11.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Ccl9, also known as C-C motif chemokine 9, is a chemokine that plays a crucial role in immune responses, particularly in the recruitment of monocytes and T cells to sites of inflammation. It is primarily expressed in various tissues including the lungs, liver, and intestines, and is instrumental in mediating the migration of immune cells during inflammatory responses. Recent studies have highlighted its involvement in various pathological conditions, such as autoimmune diseases, cancer, and chronic inflammatory disorders. Given its significant role in modulating immune activity, Ccl9 has emerged as a promising target for therapeutic interventions. Researchers are increasingly focused on developing recombinant Ccl9 proteins to better understand its molecular mechanisms and its potential as a biomarker or therapeutic agent. These recombinant proteins can be utilized in various assays to evaluate their effects on immune cell function, migration, and polarization. Additionally, exploration of Ccl9's interactions with its receptors could unveil new pathways for drug development aimed at mitigating unwanted inflammation or enhancing anti-tumor immunity. Understanding the functionality of Ccl9 through recombinant protein studies not only provides insights into its biological roles but also aids in the design of innovative strategies for treating diseases characterized by dysregulated immune responses. As research progresses, the therapeutic implications of manipulating Ccl9 signaling pathways continue to attract interest within the scientific community, offering hope for novel treatments in the realm of immunology and beyond.












