Analytical Data
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Gene name
HPR
- Application
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Alternative Names
HPR;Haptoglobin-related Protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P00739
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Expression Region
20-348aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSLYSGNDV TDISDDRFPK PPEIANGYVE HLFRYQCKNY YRLRTEGDGV YTLNDKKQWI NKAVGDKLPECEAVCGKPKN PANPVQRILG GHLDAKGSFP WQAKMVSHHN LTTGATLINE QWLLTTAKNL FLNHSENATA KDIAPTLTLY VGKKQLVEIEKVVLHPNYHQ VDIGLIKLKQ KVLVNERVMP ICLPSKNYAE VGRVGYVSGW GQSDNFKLTD HLKYVMLPVA DQYDCITHYE GSTCPKWKAP KSPVGVQPIL NEHTFCVGMS KYQEDTCYGD AGSAFAVHDL EEDTWYAAGI LSFDKSCAVA EYGVYVKVTS IQHWVQKTIA EN
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Molecular Weight
39 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HPR (Human Plasma Retinol-Binding Protein) is a critical protein involved in the transport of retinol (vitamin A) from the liver to peripheral tissues, playing a vital role in vision, growth, and immune function. Research on HPR has gained significant attention due to its implications in various health conditions, including vitamin A deficiency, obesity, and metabolic disorders. The importance of HPR in maintaining retinol homeostasis highlights the need for a deeper understanding of its structure, function, and potential as a therapeutic target. Recent advances in recombinant protein technology have facilitated the production of HPR in a laboratory setting, enabling extensive studies on its biochemical properties and interactions within biological systems. This research aims to elucidate the molecular mechanisms underlying HPR's role in retinol transport and metabolism, as well as to explore potential applications in clinical settings, such as developing strategies for managing vitamin A-related disorders. Understanding the functional dynamics of HPR through recombinant protein studies can also pave the way for innovative approaches to enhance vitamin A delivery and efficacy in various therapeutic contexts.
