Analytical Data
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Gene name
HMOX2
- Application
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Alternative Names
HMOX2;HO2;Heme oxygenase 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P30519
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Expression Region
2-316aa
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AA Sequence
SAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRKCPFYAA EQDKGALEGS SCPFRTAMAV LRKPSLQFIL AAGVALAAGL LAWYYM
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HMOX2, or Hem oxygenase 2, is an enzyme that plays a critical role in the catabolism of heme into biliverdin, carbon monoxide, and free iron. This enzyme is primarily expressed in the brain and is involved in various physiological and pathological processes, including neuroprotection, inflammation, and oxidative stress responses. Research into HMOX2 has gained attention due to its potential therapeutic implications in neurodegenerative diseases, such as Alzheimer's and Parkinson's, where oxidative stress and neuroinflammation are pivotal contributors to pathology. Moreover, HMOX2 is linked to protective mechanisms against cell death and tissue damage under stress conditions, making it a promising target for drug development aimed at enhancing cellular resilience. Recombining HMOX2 for functional studies allows researchers to investigate its activity, regulation, and interactions with other cellular pathways, providing insights into its role in health and disease. Understanding the biochemical properties and cellular effects of HMOX2 could pave the way for novel therapeutic strategies that exploit its protective functions, potentially leading to advancements in treating conditions characterized by excessive oxidative stress and inflammation.
