Analytical Data
-
基因名
IFIT1
- Application
-
别名
IFIT-1;Interferon-induced 56 kDa protein;IFI-56K;P56
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P09914
-
表达区间
1-478aa
-
氨基酸序列
MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP
-
分子量
62.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IFIT1 (Interferon-Inducible Protein 1) is a member of the interferon-stimulated gene family, playing a critical role in the innate immune response. It is primarily expressed upon viral infection and acts as a key regulator in the host's defense mechanism against pathogens. Research has shown that IFIT1 is involved in recognizing and binding to viral RNA, thus facilitating the degradation of viral genomes and inhibiting viral replication. The protein has been linked to various antiviral activities, including the modulation of signaling pathways that lead to enhanced expression of other antiviral proteins. Additionally, IFIT1 interacts with various cellular factors, suggesting its involvement in broader regulatory networks within the immune system. The study of IFIT1 recombinant proteins has garnered attention due to their potential therapeutic applications in infectious diseases and cancer. By providing clearer insights into the molecular mechanisms of IFIT1, researchers aim to develop novel strategies for bolstering immune responses or designing antiviral drugs. Understanding the structure-function relationship of IFIT1 through recombinant protein studies could pave the way for innovative treatments and a better understanding of immune regulation. Overall, the exploration of IFIT1 and its recombinant forms not only advances our fundamental knowledge of host-pathogen interactions but also holds promise for the development of targeted immunotherapies.
