Analytical Data
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基因名
HDGF
- Application
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别名
HDGF;HMG1L2;Hepatoma-derived growth factor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51858
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表达区间
1-240aa
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氨基酸序列
MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFF GTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGY QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNE KGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNST PSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
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分子量
53 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HDGF (Hepatoma-Derived Growth Factor) is a crucial protein that has gained attention in recent years due to its significant role in various cellular processes, including cell proliferation, survival, and migration. Initially identified in hepatocellular carcinoma, HDGF has been linked to tumorigenesis and is often overexpressed in various cancers, suggesting its potential as a biomarker for cancer diagnosis and prognosis. Research has shown that HDGF interacts with several signaling pathways, influencing key processes such as angiogenesis and tissue repair. Moreover, the protein is involved in the regulation of stem cell properties, making it a point of interest in regenerative medicine. Recent studies have focused on the recombinant production of HDGF to better understand its structure-function relationship and biological activity. The recombinant form allows for detailed investigations into its mechanisms of action and interactions with other cellular entities. As a result, the exploration of HDGF as a therapeutic target has become a significant area of research, with implications for developing innovative cancer treatments and enhancing tissue regeneration strategies. Understanding the nuances of HDGF biology and its interplay with different cellular contexts could provide valuable insights for therapeutic advancements in oncology and regenerative medicine. The ongoing studies aim to elucidate the full potential of HDGF, thereby paving the way for new strategies in managing cancer and tissue repair scenarios.
