Analytical Data
-
Gene name
CLEC4K
- Application
-
Alternative Names
CLEC4K；CLEC4K；C-type lectin domain family 4 member K
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9UJ71
-
Expression Region
65-328aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSPRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEP
-
Molecular Weight
32 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CLEC4K, a member of the C-type lectin receptor family, has garnered significant attention in immunology and infectious disease research. Its primary function is to recognize and bind various pathogens, thereby playing a crucial role in initiating immune responses. The receptor is predominantly expressed in dendritic cells and macrophages, where it participates in antigen presentation and the modulation of immune signaling pathways. Studies have indicated that CLEC4K can influence the differentiation of T cells and the production of cytokines, which are essential for coordinating the immune response. Recent research has focused on CLEC4K's interactions with specific pathogens, including viruses and bacteria, to understand its role in host defense mechanisms. Moreover, there is growing interest in the therapeutic potential of targeting CLEC4K for vaccine development and immunotherapy. Understanding the molecular mechanisms underlying CLEC4K's function and its contribution to immune regulation may provide insights into novel strategies for enhancing immune responses against infections and cancer. As studies continue to unravel its complexities, CLEC4K stands out as a promising candidate for further exploration in the quest for effective immune modulation.
