Analytical Data
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基因名
GSTT2
- Application
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别名
GSTT2B;GSTT2;Glutathione S-transferase theta-2B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0CG30
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表达区间
1-244aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGLELFLDLV SQPSRAVYIF AKKNGIPLEL RTVDLVKGQH KSKEFLQINS LGKLPTLKDG DFILTESSAI LIYLSCKYQT PDHWYPSDLQ ARARVHEYLG WHADCIRGTF GIPLWVQVLG PLIGVQVPEE KVERNRTAMD QALQWLEDKF LGDRPFLAGQ QVTLADLMAL EELMQPVALG YELFEGRPRL AAWRGRVEAF LGAELCQEAH SIILSILEQA AKKTLPTPSP EAYQAMLLRI ARIP
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分子量
30 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GSTT2 (Glutathione S-transferase theta 2) is a member of the glutathione S-transferase (GST) superfamily, which plays a crucial role in the detoxification of harmful compounds through conjugation with glutathione. It is primarily involved in the metabolism of xenobiotics and endogenous compounds, thereby contributing to cellular defense mechanisms against oxidative stress and chemical insults. Recent research has highlighted the significance of GSTT2 in various pathological conditions, including cancer, where its expression levels may correlate with tumor progression and drug resistance. Furthermore, GSTT2 has been implicated in the metabolism of specific chemotherapeutic agents, suggesting that it may influence the efficacy of cancer treatments. The recombinant expression of GSTT2 in laboratory settings provides a valuable tool for studying its enzymatic properties, substrate specificity, and potential as a therapeutic target. Understanding GSTT2's structure and function can aid in developing novel strategies for enhancing drug efficacy and mitigating resistance in cancer therapies. Recent advances in biotechnology and structural biology have enabled researchers to produce and characterize recombinant GSTT2, allowing for detailed investigations into its biochemical properties and interactions with potential inhibitors. As research unfolds, GSTT2 continues to emerge as a significant biomolecule with promising applications in personalized medicine and drug design, emphasizing the need for further studies to elucidate its role in human health and disease.
