Analytical Data
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Gene name
GPX2
- Application
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Alternative Names
GPX2;Glutathione peroxidase 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P18283
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Expression Region
1-190aa
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AA Sequence
MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPX2, or Glutathione Peroxidase 2, is a pivotal antioxidant enzyme that plays a crucial role in the cellular defense against oxidative stress. It is a member of the larger glutathione peroxidase family, which is essential for reducing peroxides and protecting cells from damage caused by reactive oxygen species (ROS). The study of GPX2 recombinant protein has gained significant interest due to its implications in various physiological and pathological processes, including cancer, inflammation, and neurodegenerative diseases. Elevated levels of GPX2 have been observed in certain types of tumors, suggesting its potential role in tumor progression and resistance to therapy. Additionally, GPX2 is implicated in gut health, where it contributes to intestinal epithelial integrity and immune function. By producing recombinant GPX2, researchers aim to better understand its structure-function relationships, enzyme kinetics, and interactions with other cellular components. This knowledge could lead to the development of novel therapeutic strategies targeting oxidative stress-related diseases. Furthermore, recombinant GPX2 can serve as a valuable tool in biochemical assays and therapeutic applications, as it enables the study of antioxidant mechanisms and potential interventions in oxidative damage. Understanding the functional characteristics of GPX2 through recombinant techniques is thus pivotal for advancing our comprehension of its biological significance and therapeutic potential in health and disease.
