Analytical Data
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基因名
HNRNPUL2
- Application
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别名
DKFZp762N1910; Heterogeneous nuclear ribonucleoprotein U like 2; Heterogeneous nuclear ribonucleoprotein U like protein 2; Heterogeneous nuclear ribonucleoprotein U-like protein 2; HNRL2_HUMAN; HNRNPUL 2; HNRNPUL2; HNRPUL2; OTTHUMP00000236813; SAF A2; SAF-A2; Scaffold attachment factor A2; Scaffold-attachment factor A2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q1KMD3
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表达区间
1-747aa
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氨基酸序列
MEVKRLKVTELRSELQRRGLDSRGLKVDLAQRLQEALDAEMLEDEAGGGGAGPGGACKAEPRPVAASGGGPGGDEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSKDRYGGQPLFSEKFPTLWSGARSTYGVTKGKVCFEAKVTQNLPMKEGCTEVSLLRVGWSVDFSRPQLGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGCFANFETEEVELSFSKNGEDLGVAFWISKDSLADRALLPHVLCKNCVVELNFGQKEEPFFPPPEEFVFIHAVPVEERVRTAVPPKTIEECEVILMVGLPGSGKTQWALKYAKENPEKRYNVLGAETVLNQMRMKGLEEPEMDPKSRDLLVQQASQCLSKLVQIASRTKRNFILDQCNVYNSGQRRKLLLFKTFSRKVVVVVPNEEDWKKRLELRKEVEGDDVPESIMLEMKANFSLPEKCDYMDEVTYGELEKEEAQPIVTKYKEEARKLLPPSEKRTNRRNNRNKRNRQNRSRGQGYVGGQRRGYDNRAYGQQYWGQPGNRGGYRNFYDRYRGDYDRFYGRDYEYNRYRDYYRQYNRDWQSYYYHHPQDRDRYYRNYYGYQGYR
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分子量
82.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRNPUL2, or heterogeneous nuclear ribonucleoprotein U-like protein 2, is a member of the HNRNP family, which plays crucial roles in pre-mRNA processing, RNA stability, and gene expression regulation. Recent studies have highlighted HNRNPUL2's involvement in various cellular processes, including splicing regulation, transcriptional control, and the response to stress. Given its pivotal functions, HNRNPUL2 has garnered interest as a potential biomarker and therapeutic target in various diseases, particularly cancer and neurodegenerative disorders. Research indicates that aberrant expression or mutations in HNRNPUL2 can disrupt cellular homeostasis and contribute to disease pathogenesis. Investigating the recombinant forms of HNRNPUL2 is crucial for understanding its functional mechanisms, interactions with other cellular proteins and RNAs, and its role in disease modulation. Recombinant proteins allow for detailed biochemical analyses, enabling scientists to elucidate the protein's structure-function relationships and its potential regulatory pathways. Furthermore, exploring HNRNPUL2's interactions in different cellular contexts can shed light on its contributions to cellular regulation and disease progression, paving the way for the development of novel therapeutic strategies aimed at restoring normal cellular functions in diseases where HNRNPUL2 is implicated. The comprehensive understanding of HNRNPUL2 through recombinant studies holds promise for advancing our knowledge of RNA biology and its implications in health and disease.
