Analytical Data
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Gene name
HLX1
- Application
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Alternative Names
H2.0 like homeo box 1; H2.0 like homeobox 1; H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HB24; HLX; HLX_HUMAN; Homeobox protein HB24; Homeobox protein HLX1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14774
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Expression Region
1-488aa
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AA Sequence
MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEPAQGALGCL
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Molecular Weight
77.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HLX1, or Homeobox Protein HLX, is a transcription factor belonging to the homeobox gene family, which plays a crucial role in embryonic development and cellular differentiation. It is primarily expressed in the early stages of hematopoiesis and has been linked to various processes, including organogenesis and tissue regeneration. Research indicates that HLX1 is implicated in several important biological systems, including the immune response and hematopoietic lineage specification. Abnormal expression of HLX1 has been associated with various diseases, including leukemia and other hematological disorders, suggesting its potential as a biomarker for disease diagnosis and prognosis. The study of recombinant HLX1 protein has gained traction as it allows for better understanding of its functional roles and regulatory mechanisms in cellular processes. By producing HLX1 in a recombinant form, researchers aim to investigate its interactions with other proteins, identify its downstream targets, and elucidate its involvement in specific signaling pathways. This research not only enhances our understanding of HLX1's biological significance but also opens avenues for therapeutic interventions in HLX1-associated diseases. Additionally, the generation of recombinant HLX1 provides a platform for developing novel drugs and treatment strategies, further emphasizing its relevance in both basic research and clinical applications. Overall, advancing the knowledge of HLX1 through recombinant protein studies is pivotal for understanding its contribution to health and disease, paving the way for innovative approaches in regenerative medicine and cancer therapy.
