Analytical Data
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基因名
GRA6
- Application
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别名
GRA6；TG24；Dense granule Protein 6
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q27003
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表达区间
35-150aa
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氨基酸序列
NSLGGVAVAADSGGVKQTPSETGSSGGQQEAVGTTEDYVNSSAMGGGQGDSLAEDDTTSEAAEGDVDPFPVLANEGKSEARGPSLEERIEEQGTRRRYSSVQEPQAKVPSKRTQKR
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分子量
38.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GRA6 (Glycosylphosphatidylinositol-anchored protein 6) is a crucial protein involved in the pathogenesis and immune evasion strategies of Toxoplasma gondii, an obligate intracellular parasite responsible for toxoplasmosis in humans and animals. The study of GRA6 is particularly significant due to its role in modulating host immune responses and promoting parasite survival within the host cells. Research has shown that GRA6 interacts with various host proteins, altering cellular signaling pathways and facilitating the creation of a protective niche for the parasite. Further investigations into the structural and functional properties of GRA6 have underscored its potential as a target for vaccine development and therapeutic interventions. Understanding the mechanisms by which GRA6 influences host-parasite interactions could provide valuable insights into the design of strategies aimed at controlling Toxoplasma gondii infections. Additionally, the characterization of GRA6 and its recombinant forms offers prospects for improving diagnostic methods and developing novel approaches to mitigate the impact of this widespread zoonotic disease.
