Cat: PA2000-4108

Recombinant Rat Orm1 Protein,His

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Analytical Data

  • Gene name

    Orm1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Orm1;ORM1-like Protein 3

  • Species

    Rat

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P02764

  • Expression Region

    19-205aa

  • AA Sequence

    QNPEPANITLGIPITNETLKWLSDKWFYMGAAFRDPVFKQAVQTIQTEYFYLTPNLINDTIELREFQTTDDQCVYNFTHLGVQRENGTLSKCAGAVKIFAHLIVLKKHGTFMLAFNLTDENRGLSFYAKKPDLSPELRKIFQQAVKDVGMDESEIVFVDWTKDKCSEQQKQQLELEKETKKETKKDP

  • Molecular Weight

    25.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Orm1, or ORM1 (Orosomucoid 1), is a highly glycosylated plasma protein primarily synthesized by the liver and classified as an acute-phase reactant. It has garnered significant attention in biomedical research due to its involvement in various physiological and pathological processes, including immune response, inflammation, and tissue repair. The protein is known to exhibit immunomodulatory effects, potentially influencing the outcome of diseases such as cancer, autoimmune disorders, and infectious diseases. Moreover, elevated levels of Orm1 have been associated with inflammatory conditions and certain malignancies, making it a potential biomarker for disease states. The study of recombinant Orm1 protein offers valuable insights into its structural properties, functional roles, and interactions with other biomolecules. By expressing Orm1 in heterologous systems, researchers can obtain large quantities of pure protein for detailed investigation, including its role in modulating human immune responses. Understanding the mechanisms through which Orm1 functions may open new avenues for therapeutic interventions and diagnostic applications. Overall, the research on Orm1 recombinant protein continues to enhance our knowledge of its biological significance and potential clinical implications, underscoring its importance in the context of health and disease.

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