Analytical Data
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Gene name
GLOD4
- Application
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Alternative Names
GLOD4；C17orf25;Glyoxalase domain-containing Protein 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HC38-2
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Expression Region
1-298aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMAARRALHFVFKVGNRFQTARFYRDVLGMK VLRHEEFEEGCKAACNGPYDGKWSKTMVGFGPEDDHFVAELTYNYGVGDY KLGNDFMGITLASSQAVSNARKLEWPLTEVAEGVFETEAPGGYKFYLQNR SLPQSDPVLKVTLAVSDLQKSLNYWCNLLGMKIYEKDEEKQRALLGYADN QCKLELQGVKGGVDHAAAFGRIAFSCPQKELPDLEDLMKRENQKILTPLV SLDTPGKATVQVVILADPDGHEICFVGDEAFRELSKMDPEGSKLLDDAMA ADKSDEWFAKHNKPKASG
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Molecular Weight
35 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GLOD4, also known as GLutathione-dependent Oxidoreductase Domain 4, is a member of the glutathione peroxidase family, which plays a crucial role in cellular processes by reducing reactive oxygen species (ROS) and maintaining redox homeostasis. The significance of GLOD4 has been increasingly recognized in the context of various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases, where oxidative stress is often implicated. The protein's unique structure and enzymatic properties make it a potential target for therapeutic intervention. Recent studies have revealed that GLOD4 is involved in regulating cell proliferation, apoptosis, and inflammation, indicating its multifaceted role in health and disease. Understanding the biological function of GLOD4, particularly through the development of recombinant protein for biochemical assays, allows researchers to elucidate its mechanism of action and explore its potential as a biomarker or therapeutic target. As such, the investigation into GLOD4's structure, function, and interactions at the molecular level has become an important area of research, with implications for developing novel strategies to mitigate oxidative stress-related pathologies.
