Analytical Data
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基因名
HINT3
- Application
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别名
HINT-3; HINT3; HINT3_HUMAN; Histidine triad nucleotide-binding protein 3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NQE9
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表达区间
1-182aa
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氨基酸序列
MAEEQVNRSAGLAPDCEASATAETTVSSVGTCEAAAKSPEPKDYDSTCVFCRIAGRQDPGTELLHCENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTVGKTILERNNFTDFTNVRMGFHMPPFCSISHLHLHVLAPVDQLGFLSKLVYRVNSYWFITADHLIEKLRT
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分子量
46.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HINT3 (Histidine Triad Nucleotide-binding Protein 3) is a member of the histidine triad protein family, which plays significant roles in various cellular processes, including nucleotide binding and intracellular signaling. Research into HINT3 has gained traction due to its involvement in key biological functions and its potential implications in cancer biology, particularly in the context of tumor suppression and apoptosis. Previous studies have indicated that HINT3 may act as a regulator of cell proliferation and survival, suggesting that its dysregulation could contribute to tumorigenesis. Furthermore, HINT3 has been implicated in several signaling pathways, making it a candidate for therapeutic targeting in cancer treatment. The exploration of HINT3 as a recombinant protein aims to elucidate its structure-function relationships, enhance our understanding of its biochemical properties, and develop potential applications in diagnostic and therapeutic strategies. The production and characterization of HINT3 as a recombinant protein provide a foundation for further research into its role in health and disease, potentially leading to innovative approaches in disease management, particularly in oncological settings. The ongoing investigation not only seeks to clarify the physiological functions of HINT3 but also aims to uncover its potential as a novel biomarker or therapeutic target, highlighting its relevance in modern biomedical research.












