Cat: PA1000-1244

Recombinant Human GIPC2 Protein,His

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Analytical Data

  • Gene name

    GIPC2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    GIPC2RGS19IP1;PDZ domain-containing Protein GIPC2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8TF65

  • Expression Region

    1-315aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSHMPLKLR GKKKAKSKET AGLVEGEPTG AGGGSLSASR APARRLVFHA QLAHGSATGR VEGFSSIQEL YAQIAGAFEI SPSEILYCTL NTPKIDMERL LGGQLGLEDF IFAHVKGIEK EVNVYKSEDS LGLTITDNGV GYAFIKRIKD GGVIDSVKTI CVGDHIESIN GENIVGWRHY DVAKKLKELK KEELFTMKLI EPKKAFEIEP RSKAGKSSGE KIGCGRATLR LRSKGPATVE EMPSETKAKA IEKIDDVLEL YMGIRDIDLA TTMFEAGKDK VNPDEFAVAL DETLGDFAFP DEFVFDVWGV IGDAKRRGL

  • Molecular Weight

    37 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GIPC2 (GAIP-interacting protein, C-terminus 2) is a member of the GIPC protein family, which is known for its role in various cellular processes including signal transduction, cytoskeletal dynamics, and cell adhesion. Research has highlighted GIPC2's significance in the regulation of G-protein coupled receptor (GPCR) signaling pathways, which are critical for many physiological processes and are implicated in various diseases, including cancer and neurological disorders. The expression and function of GIPC2 have been linked to cellular responses to external stimuli and its involvement in intracellular signaling cascades. Given the potential therapeutic implications of targeting GIPC2 in disease contexts, recombinant GIPC2 protein has become a focus of interest. The development and characterization of GIPC2 recombinant protein facilitate the exploration of its biochemical properties and interactions, enabling a deeper understanding of its physiological role. Such studies may provide insights into the molecular mechanisms by which GIPC2 influences cellular functions and may also pave the way for the identification of novel drug targets for treatment of various disorders related to dysregulated GPCR signaling.

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