Analytical Data
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基因名
GIPC2
- Application
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别名
GIPC2RGS19IP1;PDZ domain-containing Protein GIPC2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TF65
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表达区间
1-315aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMPLKLR GKKKAKSKET AGLVEGEPTG AGGGSLSASR APARRLVFHA QLAHGSATGR VEGFSSIQEL YAQIAGAFEI SPSEILYCTL NTPKIDMERL LGGQLGLEDF IFAHVKGIEK EVNVYKSEDS LGLTITDNGV GYAFIKRIKD GGVIDSVKTI CVGDHIESIN GENIVGWRHY DVAKKLKELK KEELFTMKLI EPKKAFEIEP RSKAGKSSGE KIGCGRATLR LRSKGPATVE EMPSETKAKA IEKIDDVLEL YMGIRDIDLA TTMFEAGKDK VNPDEFAVAL DETLGDFAFP DEFVFDVWGV IGDAKRRGL
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GIPC2 (GAIP-interacting protein, C-terminus 2) is a member of the GIPC protein family, which is known for its role in various cellular processes including signal transduction, cytoskeletal dynamics, and cell adhesion. Research has highlighted GIPC2's significance in the regulation of G-protein coupled receptor (GPCR) signaling pathways, which are critical for many physiological processes and are implicated in various diseases, including cancer and neurological disorders. The expression and function of GIPC2 have been linked to cellular responses to external stimuli and its involvement in intracellular signaling cascades. Given the potential therapeutic implications of targeting GIPC2 in disease contexts, recombinant GIPC2 protein has become a focus of interest. The development and characterization of GIPC2 recombinant protein facilitate the exploration of its biochemical properties and interactions, enabling a deeper understanding of its physiological role. Such studies may provide insights into the molecular mechanisms by which GIPC2 influences cellular functions and may also pave the way for the identification of novel drug targets for treatment of various disorders related to dysregulated GPCR signaling.












