Analytical Data
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基因名
GIPC1
- Application
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别名
GIPC1;C19orf3;GIPC;PDZ domain-containing Protein GIPC1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14908
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表达区间
1-333aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL AEALDERLGD FAFPDEFVFD VWGAIGDAKV GRY
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分子量
38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GIPC1 (G-protein coupled receptor interacting protein 1) is a member of the GIPC family that plays a crucial role in cellular signaling and intracellular transport. Recent studies have highlighted its importance in various biological processes, including cell proliferation, apoptosis, and cancer progression. GIPC1 interacts with a diverse array of proteins, modulating signaling pathways such as those involving receptor tyrosine kinases and G-proteins. Research has shown that GIPC1 is overexpressed in several types of cancer, suggesting it may serve as a potential biomarker or therapeutic target. The production of recombinant GIPC1 protein is essential for studying its functional properties and interactions at a molecular level. By utilizing techniques such as recombinant DNA technology, researchers can produce large quantities of GIPC1 for in vitro studies, enabling a deeper understanding of its role in cellular functions and disease mechanisms. Furthermore, the characterization of GIPC1 through recombinant protein studies allows for the exploration of its potential as a target for drug development, particularly in cancer therapy, where modulation of its activity could offer new treatment strategies. Overall, ongoing research into GIPC1 and its associated pathways continues to unveil its significance in both normal physiology and pathology, making it a focal point of interest in biomolecular studies.












