Analytical Data
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Gene name
SERPINB4
- Application
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Alternative Names
SERPINB4；PI11；SCCA2；Serpin B4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P48594
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Expression Region
1-390aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSMNSLSEANTKFMFDLFQQFRKSKENNI FYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDR SGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFY QTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLV NAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDV QAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRE TCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSK VLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNK TNSILFYGRFSSP
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Molecular Weight
47 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SERPINB4, also known as ovalbumin-related protein, belongs to the serpin (serine protease inhibitor) superfamily and is primarily expressed in epithelial tissues, particularly during the acute phase of inflammation and tissue repair. It plays a crucial role in modulating inflammatory responses and protecting cells from proteolytic damage. Research has shown that SERPINB4 can inhibit specific serine proteases, suggesting its involvement in regulating proteolytic pathways that affect cell migration, apoptosis, and overall tissue homeostasis. Given its association with various disease processes, including cancer and inflammatory disorders, SERPINB4 has become a focus for therapeutic research. The production of recombinant SERPINB4 protein facilitates in-depth studies of its functional properties and interactions within the cellular environment. This advance opens avenues for investigating its potential as a biomarker for disease progression, as well as its application in targeted therapies aimed at modulating immune responses and promoting tissue regeneration. Overall, the characterization of SERPINB4 as a recombinant protein is a critical step in understanding its biological significance and therapeutic potential.
