Analytical Data
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基因名
FN3KRP
- Application
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别名
FN3KRP;Ketosamine-3-kinase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HA64
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表达区间
1-309aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMEELLRRELGCSSVRATGHSGGGCISQ GRSYDTDQGRVFVKVNPKAEARRMFEGEMASLTAILKTNTVKVPKPIKVL DAPGGGSVLVMEHMDMRHLSSHAAKLGAQLADLHLDNKKLGEMRLKEAGT VGRGGGQEERPFVARFGFDVVTCCGYLPQVNDWQEDWVVFYARQRIQPQM DMVEKESGDREALQLWSALQLKIPDLFRDLEIIPALLHGDLWGGNVAEDS SGPVIFDPASFYGHSEYELAIAGMFGGFSSSFYSAYHGKIPKAPGFEKRL QLYQLFHYLNHWNHFGSGYRGSSLNIMRNLVK
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FN3KRP, or Fructose-Base Protein Kinase Regulating Protein, is a novel protein that has garnered increasing attention due to its role in regulating biological processes associated with fructose metabolism. This protein is part of the fructosamine-3-kinase (FN3K) family, which is implicated in the modification of proteins through glycation, a process where sugars bind to proteins, affecting their structure and function. Research suggests that FN3KRP may play a critical role in cellular responses to high-fructose diets, which have been linked to various metabolic disorders, including obesity, diabetes, and cardiovascular diseases. Understanding FN3KRP's function could provide insights into the pathological effects of fructose and offer potential therapeutic targets for treating these conditions. Scientists are currently exploring its expression patterns, enzymatic activity, and interaction networks to better elucidate its biological significance and potential applications in medicine. As the prevalence of fructose in diets increases globally, the study of FN3KRP could contribute to a deeper understanding of metabolic health and disease prevention strategies.
