Analytical Data
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基因名
GSTO2
- Application
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别名
GSTO2; Glutathione S-transferase omega-2; GSTO-2; EC 2.5.1.18; Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase; EC 1.8.5.1; Monomethylarsonic acid reductase; MMA(V) reductase; EC 1.20.4.2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H4Y5
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表达区间
1-243aa
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氨基酸序列
MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDFGLC
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分子量
54.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GSTO2 (Glutathione S-transferase omega 2) is a member of the glutathione S-transferase (GST) superfamily, which plays a critical role in cellular detoxification and the metabolism of xenobiotics. GSTO2 is primarily known for its function in conjugating glutathione to various electrophilic compounds, thereby aiding in their removal from the body. Research has shown that GSTO2 is involved in several cellular processes, including apoptosis, cell proliferation, and response to oxidative stress. It is also associated with various diseases, including cancer, neurodegenerative disorders, and other conditions linked to oxidative damage. The study of GSTO2 recombinantly expressed proteins has gained significance in understanding its structure-function relationships and elucidating its role in disease mechanisms. By generating and characterizing GSTO2 recombinant proteins, researchers aim to explore their enzymatic activity, substrate specificity, and interactions with other cellular components. This research could lead to insights into the development of GSTO2-targeted therapies and the identification of biomarkers for diseases where GSTO2 is implicated. Furthermore, understanding the mechanisms by which GSTO2 contributes to detoxification processes may have broader implications for pharmacology and toxicology, potentially informing the design of drugs that modulate its activity. Overall, the investigation of GSTO2 recombinant proteins represents an important avenue for advancing our comprehension of this multifunctional enzyme and its potential therapeutic applications.
