Cat: PA1000-9743

Recombinant Human AATF Protein,His

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Analytical Data

  • 基因名

    AATF

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    AATF;CHE1;DED;Protein AATF

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9NY61

  • 表达区间

    6-294aa

  • 氨基酸序列

    PLALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQE

  • 分子量

    58.8 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

AATF (Anti-apoptosis protein associated with transcription factor) is a critical protein that has garnered attention in the field of molecular biology and cancer research due to its role in regulating apoptosis and promoting cell survival. Initially identified as a transcriptional coactivator, AATF has been implicated in various cellular processes, including stress responses, cell proliferation, and differentiation. Research has shown that aberrant expression of AATF is often associated with tumorigenesis and the progression of various cancers, making it a potential biomarker and therapeutic target. The study of recombinant AATF has become increasingly important for understanding its functional properties and interactions with other cellular proteins, as well as its mechanistic role in cancer development. By producing AATF in a recombinant form, researchers can investigate its structure-function relationships, explore its signaling pathways, and evaluate its potential as a target for novel cancer therapies. This research not only aims to elucidate the molecular mechanisms underlying AATF's functions but also to assess its efficacy in preclinical models for developing targeted treatments against cancers with dysregulated AATF expression. Overall, the investigation of AATF as a recombinant protein provides insights into its biological roles and therapeutic potential, paving the way for innovative strategies to tackle cancer and other diseases linked to apoptosis dysregulation.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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