Analytical Data
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Gene name
CCDC112
- Application
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Alternative Names
CCDC112；MBC1；Coiled-coil domain-containing Protein 112
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NEF3
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Expression Region
1-446aa
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AA Sequence
MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGSGPLLHIPHRAIPTWRQGIQRRV
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Molecular Weight
66.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC112 (Coiled-Coil Domain Containing 112) is a protein that has garnered significant interest in the field of molecular biology due to its potential roles in cellular processes and disease mechanisms. Research has suggested that CCDC112 is involved in various cellular functions, including cell signaling, cytoskeletal organization, and gene regulation. Preliminary studies indicate that alterations in the expression or function of CCDC112 may be linked to pathological conditions, such as cancer and neurodegenerative diseases. Given its coiled-coil domain, CCDC112 may participate in protein-protein interactions, making it a candidate for further investigation in the context of protein networks that govern cellular homeostasis. Understanding the structure and function of CCDC112 is crucial, as it may provide insights into the molecular pathways implicated in disease progression and hold potential for therapeutic interventions. Accordingly, the development and characterization of recombinant CCDC112 protein have become a focal point for researchers aiming to delineate its biological roles and therapeutic potentials, thereby expanding our knowledge of its involvement in human health and disease. This research not only enhances our understanding of fundamental biological processes but also opens avenues for novel clinical strategies targeting CCDC112-related pathways.
