Analytical Data
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基因名
FANK1
- Application
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别名
FANK1NSE2;Fibronectin type 3 and ankyrin repeat domains Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TC84
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表达区间
1-345aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMEPQKIM PPSKPHPPVV GKVTHHSIEL YWDLEKKAKR QGPQEQWFRF SIEEEDPKMH TYGIIYTGYA TKHVVEGLEP RTLYRFRLKV TSPSGECEYS PLVSVSTTRE PISSEHLHRA VSVNDEDLLV RILQGGRVKV DVPNKFGFTA LMVAAQKGYT RLVKILVSNG TDVNLKNGSG KDSLMLACYA GHLDVVKYLR RHGASWQARD LGGCTALHWA ADGGHCSVIE WMIKDGCEVD VVDTGSGWTP LMRVSAVSGN QRVASLLIDA GANVNVKDRN GKTPLMVAVL NNHEELVQLL LDKGADASVK NEFGKGVLEM ARVFDRQSVV SLLEERKKKQ RPKKSCVC
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分子量
41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FANK1, or Focal Adhesion Kinase 1, is a critical protein involved in various cellular processes, including cell adhesion, migration, and signal transduction. Its role in cancer biology has garnered considerable attention, given its influence on tumor progression and metastasis. Research has shown that FANK1 is overexpressed in several cancers, making it a potential biomarker and therapeutic target. Scientists are investigating recombinant FANK1 proteins to better understand its functional roles and interactions within cellular pathways. The generation of these recombinant proteins facilitates the study of FANK1's structure-function relationships, enabling the identification of key domains critical for its activity. By using various expression systems, researchers can produce large quantities of purified FANK1, allowing for detailed biochemical and biophysical analyses. This research aims to elucidate the molecular mechanisms underlying FANK1's involvement in cancer and to explore its potential as a target for therapeutic intervention. The characterization of recombinant FANK1 could pave the way for novel strategies in cancer treatment, aiming to inhibit its activity or disrupt its interactions with other cellular partners. Overall, the study of FANK1 recombinant proteins represents a significant step forward in understanding the complexities of cancer biology and could hold promise for future clinical applications.
