Analytical Data
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Gene name
DEAF1
- Application
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Alternative Names
DEAF1；SPN；ZMYND5；Deformed epidermal autoregulatory factor 1 homolog
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75398
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Expression Region
1-565aa
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AA Sequence
MEDSDSAAKQLGLAEAAAVAAAAAVAAAAAAAAGGEAEEPVLSRDEDSEEDADSEAERETPRVTAVAVMAAEPGHMDMGAEALPGPDEAAAAAAFAEVTTVTVANVGAAADNVFTTSVANAASISGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETTGLKGPAAPLTPGPQSPPTPLAPGQEKGGTKYNWDPSVYDSELPVRCRNISGTLYKNRLGSGGRGRCIKQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCDDMTLSGPVRLFVPYKRRKKENELPTTPVKKDSPKNITLLPATAATTFTVTPSGQITTSGALTFDRASTVEATAVISESPAQGDVFAGATVQEASVQPPCRASHPEPHYPGYQDSCQIAPFPEAALPTSHPKIVLTSLPALAVPPPTPTKAAPPALVNGLELSEPRSWLYLEEMVNSLLNTAQQLKTLFEQAKHASTYREAATNQAKIHADAERKEQSCVNCGREAMSECTGCHKVNYCSTFCQRKDWKDHQHICGQSAAVTVQADEVHVAESVMEKVTV
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Molecular Weight
65.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DEAF1 (Deformed Epidermal Auto-Regulatory Factor 1) is a transcription factor that plays a crucial role in various biological processes, including the regulation of gene expression, neuronal development, and response to environmental stimuli. Research on DEAF1 has garnered interest due to its association with several neurological disorders, suggesting that altered DEAF1 activity may contribute to pathophysiological conditions. The study of DEAF1 recombinant protein is fundamental for understanding its structure-function relationship and potential binding interactions with other molecular partners. By producing DEAF1 as a recombinant protein, researchers can investigate its biochemical properties, elucidate its role in gene transcription regulation, and explore its interaction with specific DNA sequences and other proteins. This knowledge may pave the way for developing targeted therapeutics aimed at modulating DEAF1 activity in disease contexts. Furthermore, the use of recombinant DEAF1 provides an opportunity to study post-translational modifications and their impact on protein function. Overall, ongoing research into DEAF1 recombinant protein is expected to shed light on its molecular mechanisms and therapeutic potential, particularly in relation to neurodegenerative diseases and other conditions where DEAF1 misregulation is implicated.
