Analytical Data
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基因名
GPR182
- Application
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别名
GPR182; ADMR; G-protein coupled receptor 182
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15218
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表达区间
1-404aa
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氨基酸序列
MSVKPSWGPGPSEGVTAVPTSDLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFALYLAMFVVGLVENLLVICVNWRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGPEPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRRHCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFYDVIDCFSMLHCVINPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAAPHPEPSLSFQAHHLLPNTSPISPTQPLTPS
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分子量
46.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR182, or G protein-coupled receptor 182, is a member of the largest family of membrane proteins involved in various physiological processes, including immune response, cell signaling, and metabolism. Recent studies have highlighted its potential role in the modulation of inflammatory responses and its implications in various diseases, such as cancer and autoimmune disorders. The research on GPR182 recombinant proteins has gained traction due to the receptor's emerging significance in therapeutic development. Understanding the structural and functional characteristics of GPR182 is crucial for elucidating its mechanisms of action and for identifying potential drug targets. Generating recombinant GPR182 proteins allows researchers to investigate the receptor's binding affinity, intracellular signaling pathways, and interactions with ligands. Additionally, these studies can aid in the design of selective modulators that could serve as novel therapeutic agents. The advancement of techniques such as CRISPR gene editing and advanced protein engineering has facilitated the exploration of GPR182, paving the way for innovative strategies to manipulate its activity in clinical settings. Overall, the study of GPR182 recombinant proteins is vital for uncovering their roles in health and disease, fostering the development of new treatments targeting this receptor.
