Analytical Data
-
Gene name
GPR158
- Application
-
Alternative Names
5330427M13Rik; GP158_HUMAN; GPR158; mKIAA1136; Probable G-protein coupled receptor 158; RP11-59G22.1; RP23-133B16.1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q5T848
-
Expression Region
23-131aa
-
AA Sequence
RDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHATN
-
Molecular Weight
37.73 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR158, a member of the G protein-coupled receptor (GPCR) family, has garnered attention in recent years due to its association with various neuropsychiatric disorders and its role in modulating neurotransmission. Despite its potential significance, the functional mechanisms and signaling pathways of GPR158 remain poorly understood, primarily due to the lack of comprehensive studies and structural data. Recent research indicates that GPR158 may play a critical role in the regulation of neuronal excitability and synaptic plasticity, suggesting its involvement in cognitive functions and mood regulation. The investigation of GPR158 recombinant proteins is essential for elucidating its pharmacological properties and interactions with ligands, which could ultimately lead to the development of novel therapeutic strategies targeting neuropsychiatric conditions. Moreover, producing GPR158 as a recombinant protein allows scientists to study its structure-function relationship in detail, facilitating high-throughput screening of small molecules and the identification of potential drug candidates. Understanding GPR158's role in brain function could contribute to the advancement of treatment options for disorders such as depression, anxiety, and schizophrenia, marking a significant step forward in the field of neuropharmacology. Therefore, the research surrounding GPR158 recombinant protein is pivotal not only for basic science but also for its translational implications in developing new therapies aimed at improving mental health outcomes.
