Analytical Data
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Gene name
FABP4
- Application
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Alternative Names
FABP4;Fatty acid-binding Protein. adipocyte
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15090
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Expression Region
1-132aa
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AA Sequence
MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDVI TIKSESTFKN TEISFILGQE FDEVTADDRK VKSTITLDGG VLVHVQKWDG KSTTIKRKRE DDKLVVECVM KGVTSTRVYE RA
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Molecular Weight
15 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fatty acid-binding protein 4 (FABP4), also known as adipocyte FABP, plays a crucial role in lipid metabolism and is predominantly expressed in adipose tissue and macrophages. Its primary function involves the transport and binding of free fatty acids, which influences various metabolic processes, including insulin sensitivity, inflammation, and adipogenesis. In recent years, increasing evidence has highlighted the association of FABP4 with metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases. Researchers have begun to explore FABP4 as a potential therapeutic target due to its pivotal role in these conditions. The production and study of recombinant FABP4 proteins have enabled scientists to investigate the protein's structural and functional properties in detail, as well as to assess its interactions with various ligands and cellular pathways. Understanding the mechanistic role of FABP4 in metabolic regulation could pave the way for novel interventions to combat obesity-related diseases. By utilizing recombinant DNA technology, scientists can produce adequate amounts of this protein for in vitro and in vivo studies, further elucidating its role in systemic metabolism and its potential as a biomarker for metabolic health.
