Analytical Data
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基因名
GNG5
- Application
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别名
FLJ92393; GBG5_HUMAN; Gng5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5; OTTHUMP00000011474; OTTHUMP00000011565
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P63218
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表达区间
1-68aa
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氨基酸序列
MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKVCSFL
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分子量
33.22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GNG5, also known as Guanine nucleotide-binding protein gamma-5, is part of the G protein family that plays a crucial role in various signal transduction pathways. Research into GNG5-recombinant proteins has gained momentum due to their potential implications in understanding cellular signaling mechanisms associated with various physiological and pathological processes. GNG5 is of particular interest because it forms complexes with G protein beta subunits, influencing numerous downstream signaling pathways, including those related to cardiovascular function, neurobiology, and cancer. Furthermore, major advances in biochemical techniques have enabled the production and purification of GNG5-recombinant proteins, facilitating detailed studies on their structural and functional properties. Investigations into GNG5 could provide insights into its role in signal transduction dysregulation, which is often implicated in diseases. The ability to generate GNG5 in a recombinant form also opens avenues for exploring its potential as a therapeutic target and for developing novel drug delivery systems that could modulate G protein signaling. Collectively, the study of GNG5-recombinant proteins not only enhances our understanding of G protein-coupled receptor systems but also contributes to the broader field of molecular biology and pharmacology, aligning with ongoing efforts to elucidate the complex networks governing cellular communication and therapeutic interventions.
