Cat: PA2000-3744

Recombinant Human SLC26A5 Protein,His

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Analytical Data

  • Gene name

    SLC26A5

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    SLC26A5;PRES;Prestin

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P58743

  • Expression Region

    1-447aa

  • AA Sequence

    MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAF TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLA FAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVR LVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGF VAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAV LQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVG FSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRS LVQEGTGGKTQTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQR

  • Molecular Weight

    81.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

SLC26A5, also known as SLC26A5 or Prestin, is a gene that encodes a transmembrane protein critical for the functioning of outer hair cells (OHCs) in the cochlea, playing a significant role in hearing and sound amplification. Research into SLC26A5 has highlighted its importance in the mechanism of electromotility, where OHCs change shape in response to changes in membrane potential, thereby enhancing the sensitivity and selectivity of the auditory system. Understanding the structure and function of the SLC26A5 protein is essential for comprehending various auditory disorders and potential therapeutic interventions. Recombinant SLC26A5 proteins have been developed to study their properties in detail, facilitating investigations into their role in cellular processes and potentially providing insight into the mechanisms underlying hearing loss. These studies are crucial for unveiling the intricacies of cochlear function and may lead to advancements in regenerative medicine and hearing restoration methods.

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