Analytical Data
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Gene name
DDX19B
- Application
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Alternative Names
(DEAD box RNA helicase DEAD5)(DEAD box protein 19B)
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UMR2
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Expression Region
2-479aa
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Molecular Weight
66.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DDX19B is a member of the DExD/H-box family of RNA helicases, which play crucial roles in various cellular processes, including RNA metabolism, gene expression regulation, and viral replication. The study of DDX19B has gained attention due to its involvement in essential biological functions and its potential implications in diseases, including cancer and viral infections. Research indicates that DDX19B is essential for the nuclear export of RNA and ribonucleoprotein complexes, thereby influencing the stability and translation of mRNAs. This protein has also been implicated in the modulation of several signaling pathways, suggesting its role as a regulatory factor in cellular homeostasis. Given the increasing discovery of DDX19B's multifaceted functions, recombinant DDX19B protein has become a valuable tool for exploring its molecular mechanisms, interactions with other proteins, and its potential as a therapeutic target. Furthermore, understanding DDX19B's function may lead to novel insights into the development of strategies against diseases where DDX19B is dysregulated. Consequently, the production and characterization of recombinant DDX19B protein facilitate detailed studies on its biochemical properties and biological significance, contributing to the broader understanding of RNA helicases in health and disease.
