Analytical Data
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基因名
EFNA5
- Application
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别名
EFNA5；EPLG7；LERK7;Ephrin-A5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P52803
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表达区间
21-203aa
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氨基酸序列
QDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADDTVHESAEPSRGEN
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分子量
50.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EFNA5, or Ephrin-A5, is a member of the ephrin family of proteins that play critical roles in mediating cell-cell interactions, particularly in the nervous system and during embryonic development. This protein is involved in the regulation of cell adhesion, migration, and axon guidance, significantly influencing neural patterning and tissue architecture. Research has shown that EFNA5 interacts with Eph receptors, which are tyrosine kinases that initiate signaling pathways affecting cellular responses to environmental cues. Aberrant EFNA5 signaling has been implicated in various pathological conditions, including cancer metastasis and neurological disorders. The recombinant expression of EFNA5 in laboratory settings has enabled scientists to dissect its functional roles and mechanisms at the molecular level. By studying the biochemical properties and interactions of EFNA5, researchers aim to better understand its contributions to development and disease. The production of EFNA5 as a recombinant protein also facilitates the development of potential therapeutic strategies that could target the EFNA5-Eph receptor interaction in disease contexts, offering novel insights into its role as a biomarker or therapeutic target in cancer and neurodevelopmental disorders.
