Cat: IPD-X41814

Recombinant Human SLC25A19 Protein,His

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Analytical Data

  • Gene name

    SLC25A19

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    (Mitochondrial uncoupling protein 1)(Solute carrier family 25 member 19)

  • Species

    Human

  • Source

    E. coli

  • Tag

    N- His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9HC21

  • Expression Region

    1-320aa

  • Molecular Weight

    37.0 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SLC25A19 is a gene that encodes for a mitochondrial transporter protein involved in the transport of key metabolites, particularly in the context of cellular energy metabolism. Mutations in this gene have been linked to various metabolic disorders, including mitochondrial diseases, which can severely affect organ function and overall health. Research into SLC25A19 has gained significance due to its role in the pathophysiology of conditions such as mitochondrial encephalomyopathy, which emphasizes the importance of understanding its functional mechanisms. The recombinant protein produced from SLC25A19 is a valuable tool for investigating its transport capabilities, substrate specificity, and interactions with other mitochondrial proteins. Through detailed biochemical and structural studies, researchers aim to elucidate the molecular basis of SLC25A19 function and its implications in health and disease. Such insights are critical for developing potential therapeutic strategies targeting mitochondrial dysfunction, thereby enhancing our understanding of cellular energy homeostasis and its impact on human health.

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