Analytical Data
-
Gene name
ITLN2
- Application
-
Alternative Names
ITLN2；Intelectin-2
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8WWU7
-
Expression Region
27-325aa
-
AA Sequence
AAAS SLEMLSREFE TCAFSFSSLP RSCKEIKERC HSAGDGLYFL RTKNGVVYQT FCDMTSGGGG WTLVASVHEN DMRGKCTVGD RWSSQQGNKA DYPEGDGNWA NYNTFGSAEA ATSDDYKNPG YYDIQAKDLG IWHVPNKSPM QHWRNSALLR YRTNTGFLQR LGHNLFGIYQ KYPVKYRSGK CWNDNGPAIP VVYDFGDAKK TASYYSPYGQ REFVAGFVQF RVFNNERAAN ALCAGIKVTG CNTEHHCIGG GGFFPQGKPR QCGDFSAFDW DGYGTHVKSS CSREITEAAV LLFYR
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ITLN2, or Intestinal Trefoil Factor 2, is a member of the trefoil factor family known for its roles in mucosal protection and repair. Predominantly expressed in the intestinal epithelium, ITLN2 plays a crucial role in maintaining gut homeostasis and integrity, particularly in response to inflammatory stimuli and injury. Research surrounding ITLN2 has gained significant attention due to its potential implications in various gastrointestinal disorders, including inflammatory bowel disease (IBD) and colorectal cancer. Understanding the expression patterns and functional mechanisms of ITLN2 could pave the way for novel therapeutic strategies aimed at enhancing mucosal healing and defense. Additionally, recombinant ITLN2 protein has been explored for its biological activities, including its capacity to influence gut microbiota and modulate immune responses. The investigation into ITLN2 and its recombinant forms holds promise not only for basic science but also for clinical applications in managing mucosal diseases, thereby addressing critical gaps in gastrointestinal health and disease management. This research is underpinned by a growing recognition of the importance of trefoil factors in tissue repair processes and their potential as biomarkers for intestinal health.
