Analytical Data
-
Gene name
U60S
- Application
-
Alternative Names
(Selenium donor protein 2)(Selenophosphate synthase 2)
-
Species
Human
-
Source
Yeast
-
Tag
C- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q99611
-
Expression Region
2-448aa(U60S)
-
Molecular Weight
48.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
U60S is a recombinant protein derived from the 60S ribosomal subunit, which plays a crucial role in protein synthesis within eukaryotic cells. The interest in U60S research has surged due to its fundamental significance in understanding the mechanisms of translation, cellular regulation, and the impact of ribosomal dysfunction on diseases, including cancer and genetic disorders. Recent advances in biophysical techniques, such as cryo-electron microscopy and X-ray crystallography, have facilitated detailed structural insights into the ribosomal machinery, allowing researchers to explore how U60S interacts with various translation factors and ribosomal RNA. By studying recombinant U60S, scientists aim to elucidate its functional roles and potential interactions with antibiotics and other therapeutic agents, which could lead to the development of novel drugs targeting eukaryotic ribosomes. This research not only enhances our comprehension of fundamental biological processes but also paves the way for innovative approaches in drug design and therapeutic interventions against diseases that arise from translational errors or ribosomal malfunctions. Overall, the exploration of U60S as a model system provides valuable insights into ribosomal structure-function relationships and broadens our understanding of cellular metabolism and its implications for health and disease.
