Cat: IPD-X41803

Recombinant Human U60S Protein (Yeast),His

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Analytical Data

  • 基因名

    U60S

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    (Selenium donor protein 2)(Selenophosphate synthase 2)

  • 种属

    Human

  • 表达系统

    Yeast

  • 标签

    C- His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q99611

  • 表达区间

    2-448aa(U60S)

  • 分子量

    48.2 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

U60S is a recombinant protein derived from the 60S ribosomal subunit, which plays a crucial role in protein synthesis within eukaryotic cells. The interest in U60S research has surged due to its fundamental significance in understanding the mechanisms of translation, cellular regulation, and the impact of ribosomal dysfunction on diseases, including cancer and genetic disorders. Recent advances in biophysical techniques, such as cryo-electron microscopy and X-ray crystallography, have facilitated detailed structural insights into the ribosomal machinery, allowing researchers to explore how U60S interacts with various translation factors and ribosomal RNA. By studying recombinant U60S, scientists aim to elucidate its functional roles and potential interactions with antibiotics and other therapeutic agents, which could lead to the development of novel drugs targeting eukaryotic ribosomes. This research not only enhances our comprehension of fundamental biological processes but also paves the way for innovative approaches in drug design and therapeutic interventions against diseases that arise from translational errors or ribosomal malfunctions. Overall, the exploration of U60S as a model system provides valuable insights into ribosomal structure-function relationships and broadens our understanding of cellular metabolism and its implications for health and disease.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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