Analytical Data
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基因名
TOR1AIP2
- Application
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别名
TOR1AIP2；IFRG15；LULL1；Torsin-1A-interacting Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NFQ8
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表达区间
1-470aa
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氨基酸序列
MADSGLREPQEDSQKDLENDPSVNSQAQETTIIASNAEEAEILHSACGLSKDHQEVETEGPESADTGDKSESPDEANVGKHPKDKTEDENKQSFLDGGKGHHLPSENLGKEPLDPDPSHSPSDKVGRADAHLGSSSVALPKEASDGTGASQEPPTTDSQEAQSPGHSSAGQEGEDTLRRRLLAPEAGSHPQQTQKLEEIKENAQDTMRQINKKGFWSYGPVILVVLVVAVVASSVNSYYSSPAQQVPKNPALEAFLAQFSQLEDKFPGQSSFLWQRGRKFLQKHLNASNPTEPATIIFTAAREGRETLKCLSHHVADAYTSSQKVSPIQIDGAGRTWQDSDTVKLLVDLELSYGFENGQKAAVVHHFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLEASVGPRETEEKVRDLLWAKFTNSDTPTSFNHMDSDKLSGLWSRISHLVLPVQPVSSIEEQGCLF
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分子量
51.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TOR1AIP2, or TOR1A interacting protein 2, has garnered significant attention in the field of molecular biology due to its potential roles in various physiological and pathological processes. This protein is associated with the torsin A protein, which is implicated in DYT1 dystonia, a hereditary movement disorder. Research suggests that TOR1AIP2 may play a crucial role in the cellular mechanisms of torsin A, including its functions in protein folding, trafficking, and cellular stress responses. Dysregulation of these processes is thought to contribute to the onset of dystonia and other neurological disorders. Moreover, TOR1AIP2 may also be involved in neuroprotective pathways, and its interactions with torsin A could provide insights into therapeutic approaches for dystonia and related diseases. The study of TOR1AIP2's structure and function is essential for understanding its biological significance and the molecular underpinnings of torsin A-related disorders, potentially leading to the development of novel interventions targeting these pathways. Researchers are employing various techniques, including recombinant protein expression and purification, to investigate the molecular interactions and biological roles of TOR1AIP2, thus contributing to the broader understanding of its implications in neurobiology and disease.
