Analytical Data
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Gene name
TOR1B
- Application
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Alternative Names
TOR1B;DQ1;Torsin-1B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14657
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Expression Region
25-336aa
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AA Sequence
FEPITV GLAIGAASAI TGYLSYNDIY CRFAECCREE RPLNASALKL DLEEKLFGQH LATEVIFKAL TGFRNNKNPK KPLTLSLHGW AGTGKNFVSQ IVAENLHPKG LKSNFVHLFV STLHFPHEQK IKLYQDQLQK WIRGNVSACA NSVFIFDEMD KLHPGIIDAI KPFLDYYEQV DGVSYRKAIF IFLSNAGGDL ITKTALDFWR AGRKREDIQL KDLEPVLSVG VFNNKHSGLW HSGLIDKNLI DYFIPFLPLE YRHVKMCVRA EMRARGSAID EDIVTRVAEE MTFFPRDEKI YSDKGCKTVQ SRLDFH
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TOR1B is a member of the Target of Rapamycin (TOR) signaling pathway, which plays a crucial role in regulating cell growth, proliferation, and metabolism in response to nutrient availability and environmental cues. Research on TOR1B, particularly its role in various biological processes and diseases, has gained significant attention in recent years. This protein is associated with cellular responses to stress, aging, and cancer. The TOR signaling pathway has been identified as a critical regulator of autophagy and protein synthesis, impacting stem cell biology and tissue homeostasis. Understanding the function and regulation of TOR1B could reveal potential therapeutic targets for diseases linked to dysregulation of this pathway, such as cancer and metabolic disorders. Advances in recombinant protein technology have enabled researchers to produce and study TOR1B in detail, allowing for in-depth analysis of its structure, function, and interactions with other proteins. This knowledge is vital for elucidating the mechanisms behind TOR1B's involvement in various cellular processes and its potential as a biomarker or therapeutic target in conditions related to aberrant TOR signaling.











