Analytical Data
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Gene name
PP1446
- Application
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Alternative Names
PP1446；Insulin-like growth factor II
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P01344
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Expression Region
30-180aa
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AA Sequence
ETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
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Molecular Weight
44.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PP1446 is a recombinant protein that has garnered significant attention in the field of biomedical research due to its potential therapeutic applications. The protein is derived from a specific gene known for its role in regulating cellular processes, including proliferation and apoptosis. In recent years, the interest in PP1446 has surged as researchers have begun to explore its implications in various diseases, particularly cancer and metabolic disorders. Studies have indicated that PP1446 exhibits unique structural characteristics that enhance its stability and functionality, making it a promising candidate for drug development. Moreover, the protein has been shown to interact with key molecular pathways, influencing cellular signaling mechanisms. This has led to investigations into its ability to modulate inflammatory responses and its potential as a biomarker for disease progression. The recombinant expression of PP1446 using advanced biotechnological techniques has allowed for the generation of large quantities of the protein, facilitating further analyses. Understanding PP1446’s precise mechanisms of action could pave the way for novel therapeutic strategies, contributing to improved treatment options for patients suffering from life-threatening conditions. The ongoing research surrounding PP1446 not only highlights its biological significance but also emphasizes the need for continued exploration of recombinant proteins in the quest for innovative medical solutions.
