Cat: PA1000-798DB

Recombinant Human CXCL17 Protein,His

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Analytical Data

  • 基因名

    CXCL17

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CXCL17;VCC1;C-X-C motif chemokine 17

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q6UXB2

  • 表达区间

    22-119aa

  • 氨基酸序列

    MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL

  • 分子量

    14 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CXCL17, a member of the CXC chemokine family, has garnered attention due to its unique structural and functional characteristics. Initially identified for its role in immune response, CXCL17 is primarily expressed by various cell types, including epithelial cells and macrophages, and plays a significant role in mediating the recruitment of immune cells to sites of infection or inflammation. Research has shown that CXCL17 is involved in various pathological processes, including cancer progression, autoimmune diseases, and chronic inflammatory conditions. Its ability to bind to the chemokine receptor CXCR8 suggests a crucial role in modulating immune responses. Recent studies have focused on the production of recombinant CXCL17 protein to better understand its biological functions and potential therapeutic applications. By employing recombinant DNA technology, researchers aim to generate a stable supply of CXCL17 for in vitro and in vivo studies. These investigations seek to elucidate the signaling pathways activated by CXCL17, its role in tumor microenvironments, and its potential as a biomarker for disease progression. Additionally, understanding the structure-activity relationship of CXCL17 could pave the way for novel drug development aimed at manipulating its activity for therapeutic benefits. Given the increasing recognition of chemokines in the context of cancer immunotherapy and other disease treatments, the study of CXCL17 and its recombinant protein will likely contribute important insights into the intricate interplay between the immune system and disease pathogenesis.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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