Analytical Data
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Gene name
CTSW
- Application
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Alternative Names
CTSW;Cathepsin W
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P56202
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Expression Region
22-376aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSIRGPLRA QDLGPQPLEL KEAFKLFQIQ FNRSYLSPEE HAHRLDIFAH NLAQAQRLQE EDLGTAEFGV TPFSDLTEEE FGQLYGYRRA AGGVPSMGRE IRSEEPEESV PFSCDWRKVA GAISPIKDQK NCNCCWAMAA AGNIETLWRI SFWDFVDVSV QELLDCGRCG DGCHGGFVWD AFITVLNNSG LASEKDYPFQ GKVRAHRCHP KKYQKVAWIQ DFIMLQNNEH RIAQYLATYG PITVTINMKP LQLYRKGVIK ATPTTCDPQL VDHSVLLVGF GSVKSEEGIW AETVSSQSQP QPPHPTPYWI LKNSWGAQWG EKGYFRLHRG SNTCGITKFP LTARVQKPDM KPRVSCPP
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Molecular Weight
42 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTSW, or Cathepsin W, is a member of the cathepsin family of cysteine proteases, which play crucial roles in various biological processes, including apoptosis, antigen processing, and tissue remodeling. The study of CTSW recombinant protein has gained significant attention due to its involvement in immune responses and its potential implications in diseases such as cancer and autoimmune disorders. Researchers have been particularly interested in characterizing its enzymatic activity, substrate specificity, and regulatory mechanisms. Recombinant technology allows for the production of CTSW in vitro, enabling detailed studies of its function and interactions with other cellular proteins and pathways. Understanding the structural and functional properties of CTSW could provide insights into its role in health and disease, paving the way for novel therapeutic strategies aimed at modulating its activity. As CTSW's exact physiological functions and regulatory networks remain partially elucidated, ongoing research aims to explore its potential as a biomarker for disease progression and as a target for drug development. Additionally, the manipulation of CTSW activity through recombinant proteins may offer new avenues for treating conditions linked to dysregulated protease activity, emphasizing the importance of this enzyme in biomedical research.
