Analytical Data
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基因名
KIR3DL3
- Application
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别名
KIR3DL3；CD158Z；KIR3DL7；KIRC1；Killer cell immunoglobulin-like receptor 3DL3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N743
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表达区间
1-322aa
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氨基酸序列
MSLMVVSMAC VGFFLLEGPW PHVGGQDKPF LSAWPGTVVS EGQHVTLQCR SRLGFNEFSL SKEDGMPVP ELYNRIFRNS FLMGPVTPAH AGTYRCCSSH PHSPTGWSAP SNPVVIMVTG VHRKPSLLA HPGPLVKSGE TVILQCWSDV RFERFLLHRE GITEDPLRLV GQLHDAGSQV NYSMGPMTP ALAGTYRCFG SVTHLPYELS APSDPLDIVV VGLYGKPSLS AQPGPTVQAG ENVTLSCSS RSLFDIYHLS REAEAGELRL TAVLRVNGTF QANFPLGPVT HGGNYRCFGS FRALPHAWS DPSDPLPVSV TGNSRHL
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIR3DL3 is a member of the Killer Immunoglobulin-like Receptor (KIR) family, which plays a crucial role in the immune response, particularly in the regulation of natural killer (NK) cells and T cell activity. As a receptor expressed on the surface of immune cells, KIR3DL3 interacts with various ligands, impacting the recognition and elimination of infected or cancerous cells. Research has indicated that KIR3DL3 may influence the progression of diseases such as viral infections and cancer by modulating immune responses. The study of KIR3DL3 recombinant proteins offers valuable insights into its structure, function, and potential therapeutic applications. By generating recombinant KIR3DL3, researchers can examine its binding affinity and specificity to ligands, elucidate the mechanisms underlying immune regulation, and assess its role in immune evasion by pathogens. Furthermore, understanding KIR3DL3 could lead to the development of novel immunotherapeutic strategies aimed at enhancing anti-tumor immunity or restoring immune function in chronic infections. Thus, the investigation of KIR3DL3 recombinant protein holds significant promise for advancing our knowledge of immune regulation and developing targeted therapies for various diseases.
