Analytical Data
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Gene name
KIR3DL3
- Application
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Alternative Names
KIR3DL3；CD158Z；KIR3DL7；KIRC1；Killer cell immunoglobulin-like receptor 3DL3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N743
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Expression Region
1-322aa
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AA Sequence
MSLMVVSMAC VGFFLLEGPW PHVGGQDKPF LSAWPGTVVS EGQHVTLQCR SRLGFNEFSL SKEDGMPVP ELYNRIFRNS FLMGPVTPAH AGTYRCCSSH PHSPTGWSAP SNPVVIMVTG VHRKPSLLA HPGPLVKSGE TVILQCWSDV RFERFLLHRE GITEDPLRLV GQLHDAGSQV NYSMGPMTP ALAGTYRCFG SVTHLPYELS APSDPLDIVV VGLYGKPSLS AQPGPTVQAG ENVTLSCSS RSLFDIYHLS REAEAGELRL TAVLRVNGTF QANFPLGPVT HGGNYRCFGS FRALPHAWS DPSDPLPVSV TGNSRHL
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Molecular Weight
34 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KIR3DL3 is a member of the Killer Immunoglobulin-like Receptor (KIR) family, which plays a crucial role in the immune response, particularly in the regulation of natural killer (NK) cells and T cell activity. As a receptor expressed on the surface of immune cells, KIR3DL3 interacts with various ligands, impacting the recognition and elimination of infected or cancerous cells. Research has indicated that KIR3DL3 may influence the progression of diseases such as viral infections and cancer by modulating immune responses. The study of KIR3DL3 recombinant proteins offers valuable insights into its structure, function, and potential therapeutic applications. By generating recombinant KIR3DL3, researchers can examine its binding affinity and specificity to ligands, elucidate the mechanisms underlying immune regulation, and assess its role in immune evasion by pathogens. Furthermore, understanding KIR3DL3 could lead to the development of novel immunotherapeutic strategies aimed at enhancing anti-tumor immunity or restoring immune function in chronic infections. Thus, the investigation of KIR3DL3 recombinant protein holds significant promise for advancing our knowledge of immune regulation and developing targeted therapies for various diseases.
