Analytical Data
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基因名
EME1
- Application
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别名
MMS4 homolog ;hMMS4
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96AY2
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表达区间
1-583aa
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分子量
80.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EME1 (Essential Microtubule-Associated Protein E1) is a vital component in the maintenance of genomic stability, particularly during DNA repair processes and cell division. It plays a crucial role in the homologous recombination pathway, assisting in the repair of double-strand breaks and ensuring proper chromosome segregation. Studies have increasingly highlighted the importance of EME1 in various cellular contexts, including its potential interactions with other proteins involved in the DNA damage response. Aberrations in EME1 expression or function can lead to genomic instability and have been implicated in several types of cancers. Researchers have focused on characterizing the structural and functional aspects of EME1 to better understand its mechanisms of action and regulatory pathways. The recombinant production of EME1 protein allows for in-depth biochemical analyses, facilitating the investigation of its interaction partners and the elucidation of its role in cellular processes. Understanding EME1's function may open avenues for developing targeted therapies that exploit its role in DNA repair mechanisms, particularly in tumors exhibiting defects in these pathways. As such, EME1 represents a promising target for further research aimed at elucidating its multifaceted roles in maintaining genome integrity and potential implications in cancer treatment strategies.
