Analytical Data
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Gene name
EME1
- Application
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Alternative Names
MMS4 homolog ;hMMS4
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96AY2
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Expression Region
1-583aa
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Molecular Weight
80.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EME1 (Essential Microtubule-Associated Protein E1) is a vital component in the maintenance of genomic stability, particularly during DNA repair processes and cell division. It plays a crucial role in the homologous recombination pathway, assisting in the repair of double-strand breaks and ensuring proper chromosome segregation. Studies have increasingly highlighted the importance of EME1 in various cellular contexts, including its potential interactions with other proteins involved in the DNA damage response. Aberrations in EME1 expression or function can lead to genomic instability and have been implicated in several types of cancers. Researchers have focused on characterizing the structural and functional aspects of EME1 to better understand its mechanisms of action and regulatory pathways. The recombinant production of EME1 protein allows for in-depth biochemical analyses, facilitating the investigation of its interaction partners and the elucidation of its role in cellular processes. Understanding EME1's function may open avenues for developing targeted therapies that exploit its role in DNA repair mechanisms, particularly in tumors exhibiting defects in these pathways. As such, EME1 represents a promising target for further research aimed at elucidating its multifaceted roles in maintaining genome integrity and potential implications in cancer treatment strategies.
