Analytical Data
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基因名
esxT
- Application
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种属
Mycobacteroides abscessus
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A0A1N0NKG2
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表达区间
1-96aa
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分子量
18.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of esxT, a gene found within the ESX-1 secretion system of mycobacteria, particularly Mycobacterium tuberculosis, has garnered significant attention in recent years due to its critical role in host-pathogen interactions. This gene encodes a protein that is part of a family of effector proteins secreted by the ESX-1 system, which is essential for the virulence and pathogenicity of mycobacteria. Understanding the function of esxT is particularly important because it assists the bacterium in evading the host's immune response, thereby facilitating infection and persistence. Moreover, esxT has been implicated in the modulation of inflammatory responses, further contributing to the bacterium's ability to survive within host macrophages. Research into this protein can provide valuable insights into the mechanisms of tuberculosis pathogenesis, aiding the development of novel therapeutic strategies and vaccines. As tuberculosis remains a major global health threat, exploring the biological functions and interactions associated with esxT could lead to breakthroughs in its treatment and prevention, making it a focal point for microbiological and immunological studies.
