Analytical Data
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Gene name
CCDC88A
- Application
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Alternative Names
(Akt phosphorylation enhancer)(APE)(Coiled-coil domain-containing protein 88A)(G alpha-interacting vesicle-associated protein)(GIV)(Girders of actin filament)(Hook-related protein 1)(HkRP1)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q3V6T2
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Expression Region
1713-1823aa
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Molecular Weight
16.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC88A, or coiled-coil domain containing 88A, is a protein that has garnered attention in recent years due to its potential roles in various cellular processes, including cell signaling, migration, and cytoskeletal dynamics. Studies have suggested that CCDC88A might be involved in the regulation of cellular responses to extracellular stimuli, influencing both normal cellular functions and pathological conditions. In cancer research, for example, aberrant expression or mutations of CCDC88A have been linked to tumor progression and metastasis, highlighting its importance as a potential biomarker or therapeutic target. Furthermore, CCDC88A is known to interact with several key signaling molecules and pathways, which adds to its complexity and importance within cellular networks. The production of recombinant CCDC88A proteins enables researchers to study its structural properties, interaction with other proteins, and functional implications in vitro. This research can provide valuable insights into the biological mechanisms underlying diseases and may also aid in the development of novel therapeutic approaches. Understanding the precise roles of CCDC88A in various contexts is essential for revealing its potential as a target for drug development and for elucidating its contributions to human health and disease.











