Analytical Data
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基因名
GDF6
- Application
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别名
GDF6；BMP13；GDF16；Growth/differentiation factor 6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6KF10
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表达区间
336-455aa
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氨基酸序列
TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
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分子量
13.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GDF6 (Growth Differentiation Factor 6) is a member of the TGF-β superfamily and plays a crucial role in various biological processes, including embryonic development, tissue differentiation, and regeneration. It is particularly important in the development of the skeletal system, where it influences chondrogenesis and bone formation. The study of recombinant GDF6 protein has garnered significant attention due to its potential therapeutic applications in regenerative medicine and orthopedics. Researchers are investigating its role in cartilage repair and bone healing, especially in conditions such as osteoarthritis and other degenerative joint diseases. Additionally, GDF6 has been implicated in the regulation of signaling pathways that govern cellular proliferation and apoptosis, making it a candidate for cancer research. The recombinant form of GDF6 allows for detailed studies of its function, interactions with other proteins, and potential impact on cellular behavior in vitro and in vivo. Understanding the molecular mechanisms underlying GDF6 activity could lead to innovative strategies for enhancing tissue regeneration and developing novel treatments for skeletal disorders. Furthermore, exploring its effects in various biological contexts can provide insights into its broader implications in health and disease. Therefore, the characterization and application of GDF6 recombinant protein represent a promising frontier in biomedical research, aiming to leverage its unique properties for therapeutic developments.
