Analytical Data
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基因名
ITGAM
- Application
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别名
(CD11 antigen-like family member B)(CR-3 alpha chain)(Cell surface glycoprotein MAC-1 subunit alpha)(Leukocyte adhesion receptor MO1)(Neutrophil adherence receptor)(CD antigen CD11b)
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种属
Human
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表达系统
E. coli
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标签
N- His-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P11215
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表达区间
46-150aa
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分子量
57.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ITGAM, also known as integrin alpha M, is a protein that plays a crucial role in the immune response by regulating the adhesion and migration of leukocytes. Its involvement in various inflammatory and autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis, has garnered significant research interest. Recent studies have aimed to explore the structural and functional properties of ITGAM, including its interactions with other proteins and cells within the immune system. The recombination of ITGAM protein has enabled researchers to delve deeper into its mechanisms of action, facilitating potential therapeutic applications. By producing recombinant ITGAM, scientists can investigate the protein's behavior in vitro, elucidating its role in immune cell signaling and migration. Furthermore, understanding how ITGAM contributes to disease pathology can unlock new avenues for targeted therapies, providing hope for patients with chronic inflammatory conditions. This ongoing research underscores the importance of ITGAM as a key player in immune regulation and highlights the potential for recombinant proteins in advancing our knowledge of immune-related disorders.
