Analytical Data
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基因名
GDF3
- Application
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别名
GDF3；Growth/differentiation factor 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NR23
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表达区间
251-364aa
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氨基酸序列
AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GDF3, or Growth Differentiation Factor 3, is a member of the transforming growth factor-beta (TGF-β) superfamily, which plays critical roles in various biological processes, including embryonic development, cell differentiation, and tissue homeostasis. Initially identified in the context of embryonic stem cell research, GDF3 has garnered attention for its involvement in several key developmental pathways and its potential implications in regenerative medicine and cancer biology. Studies have demonstrated that GDF3 acts as a negative regulator of the TGF-β signaling pathway, influencing pluripotency and differentiation of stem cells. Its expression patterns are particularly prominent in early embryonic stages, suggesting a significant role in the maintenance and regulation of stem cell characteristics. Recent research has also highlighted GDF3’s potential as a biomarker in various cancers, further emphasizing the need for understanding its molecular mechanisms and interactions. The recombinant GDF3 protein is being increasingly utilized in laboratory studies to elucidate its functional roles, manipulate stem cell properties, and explore its therapeutic potentials. Understanding GDF3’s biological functions can provide valuable insights into developmental biology, cancer treatment strategies, and regenerative therapies, making it a noteworthy target for ongoing scientific inquiry.
