Analytical Data
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Gene name
GPR65
- Application
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Alternative Names
(G-protein coupled receptor 65)(T-cell death-associated gene 8 protein)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IYL9
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Expression Region
1-337aa
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Molecular Weight
40.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR65, also known as the G protein-coupled receptor 65, is a member of the G protein-coupled receptor (GPCR) family, which plays a crucial role in various physiological processes by mediating cellular signaling pathways. It is primarily expressed in immune cells and is implicated in the regulation of inflammation and immune responses. Research has shown that GPR65 can influence T cell differentiation and activation, making it a potential target for therapeutic interventions in autoimmune diseases and cancer. The recombinant protein of GPR65 is generated to study its structure-function relationships, signaling mechanisms, and interactions with ligands. By characterizing the recombinant GPR65, scientists aim to elucidate its role in modulating immune responses and to identify potential drug targets. Moreover, understanding how GPR65 operates at a molecular level could provide insights into the development of drugs that can selectively modulate its activity. This research is essential for translating basic scientific discoveries into clinical applications, thereby enhancing our ability to treat diseases associated with dysregulated immune function. The production and analysis of recombinant GPR65 thus represent a significant step in expanding our knowledge of GPCRs and their roles in health and disease.
