Analytical Data
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基因名
Chil4
- Application
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别名
Chitinase-3-like protein 4 Secreted protein Ym2
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种属
Mouse
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表达系统
HEK293
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标签
C- hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q91Z98
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表达区间
22-402aa
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分子量
71.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Chil4, also known as CHIL4 (Chimeric Antigen Receptor Inducible Lymphocyte 4), is a member of the transcription factor family implicated in various biological processes, including cell differentiation, proliferation, and immune responses. Its expression is especially crucial during lymphocyte development, making it relevant in the context of immune-related diseases and therapies. Recent research has highlighted its role in regulating genes associated with T-cell activation and differentiation, suggesting a potential therapeutic target for enhancing immune responses in cancer and chronic infections. Additionally, the reconstitution of Chil4 as a recombinant protein allows for detailed biochemical and structural studies, facilitating a deeper understanding of its functional dynamics. This research aims to elucidate the mechanisms of Chil4 in immune regulation, potentially leading to innovative treatments leveraging immune system modulation, especially in oncological settings. Furthermore, exploring Chil4's interactions with other proteins could unveil novel pathways and regulatory networks critical for immune surveillance and response, underscoring its significance in both basic and applied biomedical research. As the field progresses, understanding the precise roles and mechanisms of Chil4 will be essential for developing targeted therapies that harness the immune system's full potential in combating diseases.
